IPP team: Photonics Instrumentation and Processes

Difference between revisions of "GIOUX Sylvain"

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(Created page with "__NOTOC__ <big>'''Team leader'''</big> =Personal information= <big>'''Position :''' Senior Research Scientist</big> right <br /><br /> Cronenbour...")
 
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__NOTOC__
 
__NOTOC__
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<big>'''Team leader'''</big> 
 
  
 
=Personal information=
 
=Personal information=
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<big>'''Position :''' Senior Research Scientist</big> [[File:PMontgomery.PNG|right]] <br /><br />
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<big>'''Position :''' Professor</big> [[File:SGioux.jpg|right|125px]] <br /><br />  
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Cronenbourg
 
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*Office : 122, Bât28
 
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*Adress : ICube laboratory, Unistra-CNRS UMR 7357, 23 Rue du Loess, F-67037 Strasbourg, France.
 
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*Téléphone :  +33 3 88 10 62 31 <br />
 
 
Illkirch
 
Illkirch
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*Office : B146
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*Office : B133
 
*Adress : ICube laboratory, Télécom Physique Strasbourg, Pôle API - 300, boulevard Sébastien Brant - CS 10413, F-67412 ILLKIRCH Cedex
 
*Adress : ICube laboratory, Télécom Physique Strasbourg, Pôle API - 300, boulevard Sébastien Brant - CS 10413, F-67412 ILLKIRCH Cedex
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*Phone :  +33 3 68 85 46 24 <br />
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*Phone :  +33 3 68 85 46 27 <br />
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Mail : [mailto:paul.montgomery@icube.unistra.fr paul.montgomery@icube.unistra.fr]
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Mail : [mailto:sylvain.gioux@icube.unistra.fr sylvain.gioux@icube.unistra.fr]
  
 
=Research themes=
 
=Research themes=
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My main research themes consist of:
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Within the team, I am responsible for developing the theme “Photonics Instrumentation for Health”. The objective of this theme is to develop new applications based on photonics methods to solve longstanding problems related to health.
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* Photonic instrumentation for optical metrology.
 
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* Interference microscopy for the characterization of materials, 4D microscopy and high resolution tomography of transparent and diffuse layers.
 
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* Optical far field nanoscopy for the characterization of nanostructures.
 
  
  
 
=Main research projects =
 
=Main research projects =
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* Optical metrology: techniques and instrumentation for enriching the information available from materials by high resolution 3D optical microscopy (comparative measurements, multidimensional algorithms for fringe and measurement processing and …).
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In this project, we are interested in developing novel imaging methods based on the fundamental principles of optics with the objective of providing objective metrics to healthcare professionals during surgical procedures. In particular, we are actively working on quantitative diffuse optical imaging methods, with two main axes of development: fluorescence imaging and endogenous optical properties imaging. We previously developed these methods at a fundamental level and translated them during animal and first-in-human studies. We particularly focus on the robust extraction of optical parameters from scattering media (e.g. fluorescence, optical properties, oxygen saturation) from real-time images and the conditions necessary for their utilization during surgical procedures.
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* 4D microscopy (3D + t): instrumentation for real time structural measurement using high speed cameras and FPGA image processing.
 
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* High resolution tomography: high resolution white light interferometry (immersion Linnik) for characterizing internal structure of transparent and diffusing layers (polymers, biomaterials, collöds, DOE’s…).
 
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* 3D optical nanoscopy: new concepts for characterizing nanostructures using unmarked far field optical nanoscopy.
 
  
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The aims of my research work are to develop new techniques in optical microscopy and nanoscopy in order to improve the 3D measurement time 3D (<1 s per 3D image) and the lateral resolution  (<200 nm) and to enrich the amount of information available (nanostructures, optical and physical properties…). The method used consists of white light interferometry because of its very high axial sensitivity (<1 nm), its non-invasive character, the large quantity of data available and this without having to use labelling with the sample (such as the use of fluorophores or nanoparticles).
+
Our current research activities focus on the quantitative measurement of fluorescence and optical properties, over a large field-of-view (> 100 cm²) and in real-time. We develop acquisition and processing methods, as well as design and fabricate new imaging systems compatible with future clinical use. We are interested in several instrument types, from large open surgery systems to flexible endoscopy. Moreover, we investigate the relationship between optical parameters (e.g. fluorescence, optical properties, oxygen saturation) and biological / physiological parameters linked to the development of conditions based on animal models. Finally, we perform the translation of the most promising technologies towards first-in-human trials.
  
 
=Curriculum=
 
=Curriculum=
 
{| class="wikitable"
 
{| class="wikitable"
 
|-
 
|-
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! Years !! Qualifications and positions
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! Années / Years !! Postes occupés / Positions
 
|-
 
|-
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| 1997-présent || Chercheur CNRS Laboratoires ICube (UMR 7357), InESS (UMR 7357) et PHASE (UPR 292), Strasbourg, France.
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| 2015-présent || Professor - University of Strasbourg, France
 
|-
 
|-
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| 1991-1996 || Chercheur CNRS - Laboratoire CEM2 (UMR 5507), Montpellier, France.
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| 2013-2015 || Assistant Professor of Medicine, Harvard Medical School, Boston, USA
 
|-
 
|-
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| 1987-1990 || Post-doctorant (Royal Society UK et contractuel) - Laboratoire CEM2  (UMR 5507), Montpellier, France.
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| 2012-2013 || Instructor in Medicine, Harvard Medical School, Boston, USA
 
|-
 
|-
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| 1995 || HDR, CEM2 (UMR 5507), Université Montpellier II, Montpellier, France.
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| 2012-2015 || Principal Investigator / Laboratory Director, BIDMC, Boston, USA
 
|-
 
|-
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| 1987 || Ph.D. Loughborough University of Technology (LUT), Loughborough, UK, "Forward looking innovations in electronic speckle pattern interferometry”.
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| 2011-2012 || Research Fellow, , Harvard Medical School & BIDMC, Boston, USA
 
|-
 
|-
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| 1983 || M.Sc. (équivalent Masters) en métrologie optique, LUT, Loughborough, UK.
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| 2009-2011 || Chef de Projet Optique, CEA-LETI, Grenoble, France                   
 +
|}
 +
 
 +
{| class="wikitable"
 
|-
 
|-
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| 1981 || B.Sc. with honours (Licence) en physique appliquée (note : 2.1) LUT, Loughborough, UK.                     
+
! Années / Years !! Diplômes / Qualifications
 +
|-
 +
| 2014 || Habilitation à diriger des recherches, Strasbourg, France
 +
|-
 +
| 2009 || Ph.D. in Biomedical Engineering, Boston University, USA
 +
|-
 +
| 2005 || M.S. in Photonics, Boston University, USA
 +
|-
 +
| 2005 || Diplôme d’ingénieur, ENSEEIHT, Toulouse, France
 +
|-
 +
| 2002 || DUT Mesures Physiques             
 
|}
 
|}
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I am presently a Senior Research Scientist working for the CNRS and head of the IPP team (Photonics Instrumentation and Processes) at the ICube Laboratory, Strasbourg, France.
 
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My basic training is in applied physics, but with a specialization in photonic instrumentation for optical metrology. I have since specialized in high resolution optical microscopy and interferometry for the characterization of materials. Although I work mainly in engineering science, I am a physicist at heart and also an amateur philosopher of science. I am very interested in defending a sound philosophical basis for science as well as in training young researchers.
 
  
 
=Enseignement=
 
=Enseignement=
 
{| class="wikitable"
 
{| class="wikitable"
 
|-
 
|-
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| 2010-today || optical microscopy: from imaging to physics at the nanometer scale, professional training at the CMOI/SFO conference (France, every 2 years).
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| 2015-présent || Physique et Photonique - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  || Bases Physiques de l'Imagerie in vivo - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  || Traitement du Signal 1D - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  || Nanophotonique : Méthodes et Applications - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  || Techniques Instrumentales pour la Santé - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  || Bases Physiques de l’RM et de l’imagerie Optique in vivo - Télécom Physique Strasbourg, Illkirch, France
 +
|-
 +
| 2015-présent  ||Formation des Images Médicales - Télécom Physique Strasbourg, Illkirch, France
 +
 
 +
|-
 +
| 2012-2015  || BE/EC765: Introduction to Biomedical Optics and Biophotonics - Department of Biomedical Engineering / Boston University, Boston, MA
 
|-
 
|-
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| 2006-2007 || optical metrology, 3rd year engineers (Masters, photonics option), Télécom Physique Strasbourg, Illkirch (France, 3h/yr).
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| 2013-2014  || Short Course on Computational Biophotonics Summer - Beckman Laser Institute / University of California, Irvine, CA
 
|-
 
|-
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| 2000-today  || scientific communication and research culture, transversal training doctoral students, ED-MSII, Strasbourg University, Strasbourg (France, 22h/yr).
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| 2013 || BE517: Optical Microscopy of Biological Materials - Department of Biomedical Engineering / Boston University, Boston, MA
 
|-
 
|-
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| 2008-today  || teaching in English, transversal training doctoral students,   European Doctoral College, Strasbourg University, Strasbourg (France, 18h/yr).
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| 2011 || Introduction to Molecular Imaging - Joint Program in Nuclear Medicine / Harvard Medical School, Boston, MA
 
|-
 
|-
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| 1983-today || optical metrology, microscopy and the characterization of materials, scientific invited seminars (international, >30).
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| 2006  || BE209: Principles of Molecular Cell Biology and Biotechnology - Department of Biomedical Engineering / Boston University, Boston, MA
 
|}
 
|}
  
 
= Skills =
 
= Skills =
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* Interference microscopy
+
* Diffuse optical imaging
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* Far field optical nanoscopy
+
* Biomedical Optics
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* Interferometry, optical metrology
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* Biophotonic
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* Photonics instrumentation
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* Clinical translation
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* Characterization of materials by optical microscopy.
 
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* LabView.
 
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* Amateur philosopher of science
 
  
 
=Publications=
 
=Publications=
−
<anyweb>http://icube-publis.unistra.fr/?author=montgomery&title=&team=&national=&project=&year1=1979&year2=2015&fancybox-frame1418063188956=</anyweb>
+
<anyweb>http://icube-publis.unistra.fr/?author=gioux&title=&team=&national=&project=&year1=1979&year2=2015&fancybox-frame1418063188956=</anyweb>

Revision as of 16:54, 5 November 2015


Personal information

Position : Professor

SGioux.jpg



Illkirch

  • Office : B133
  • Adress : ICube laboratory, Télécom Physique Strasbourg, Pôle API - 300, boulevard Sébastien Brant - CS 10413, F-67412 ILLKIRCH Cedex
  • Phone : +33 3 68 85 46 27

Mail : sylvain.gioux@icube.unistra.fr

Research themes

Within the team, I am responsible for developing the theme “Photonics Instrumentation for Health”. The objective of this theme is to develop new applications based on photonics methods to solve longstanding problems related to health.


Main research projects

In this project, we are interested in developing novel imaging methods based on the fundamental principles of optics with the objective of providing objective metrics to healthcare professionals during surgical procedures. In particular, we are actively working on quantitative diffuse optical imaging methods, with two main axes of development: fluorescence imaging and endogenous optical properties imaging. We previously developed these methods at a fundamental level and translated them during animal and first-in-human studies. We particularly focus on the robust extraction of optical parameters from scattering media (e.g. fluorescence, optical properties, oxygen saturation) from real-time images and the conditions necessary for their utilization during surgical procedures.

Our current research activities focus on the quantitative measurement of fluorescence and optical properties, over a large field-of-view (> 100 cm²) and in real-time. We develop acquisition and processing methods, as well as design and fabricate new imaging systems compatible with future clinical use. We are interested in several instrument types, from large open surgery systems to flexible endoscopy. Moreover, we investigate the relationship between optical parameters (e.g. fluorescence, optical properties, oxygen saturation) and biological / physiological parameters linked to the development of conditions based on animal models. Finally, we perform the translation of the most promising technologies towards first-in-human trials.

Curriculum

Années / Years Postes occupés / Positions
2015-présent Professor - University of Strasbourg, France
2013-2015 Assistant Professor of Medicine, Harvard Medical School, Boston, USA
2012-2013 Instructor in Medicine, Harvard Medical School, Boston, USA
2012-2015 Principal Investigator / Laboratory Director, BIDMC, Boston, USA
2011-2012 Research Fellow, , Harvard Medical School & BIDMC, Boston, USA
2009-2011 Chef de Projet Optique, CEA-LETI, Grenoble, France
Années / Years Diplômes / Qualifications
2014 Habilitation à diriger des recherches, Strasbourg, France
2009 Ph.D. in Biomedical Engineering, Boston University, USA
2005 M.S. in Photonics, Boston University, USA
2005 Diplôme d’ingénieur, ENSEEIHT, Toulouse, France
2002 DUT Mesures Physiques

Enseignement

2015-présent Physique et Photonique - Télécom Physique Strasbourg, Illkirch, France
2015-présent Bases Physiques de l'Imagerie in vivo - Télécom Physique Strasbourg, Illkirch, France
2015-présent Traitement du Signal 1D - Télécom Physique Strasbourg, Illkirch, France
2015-présent Nanophotonique : Méthodes et Applications - Télécom Physique Strasbourg, Illkirch, France
2015-présent Techniques Instrumentales pour la Santé - Télécom Physique Strasbourg, Illkirch, France
2015-présent Bases Physiques de l’RM et de l’imagerie Optique in vivo - Télécom Physique Strasbourg, Illkirch, France
2015-présent Formation des Images Médicales - Télécom Physique Strasbourg, Illkirch, France
2012-2015 BE/EC765: Introduction to Biomedical Optics and Biophotonics - Department of Biomedical Engineering / Boston University, Boston, MA
2013-2014 Short Course on Computational Biophotonics Summer - Beckman Laser Institute / University of California, Irvine, CA
2013 BE517: Optical Microscopy of Biological Materials - Department of Biomedical Engineering / Boston University, Boston, MA
2011 Introduction to Molecular Imaging - Joint Program in Nuclear Medicine / Harvard Medical School, Boston, MA
2006 BE209: Principles of Molecular Cell Biology and Biotechnology - Department of Biomedical Engineering / Boston University, Boston, MA

Skills

  • Diffuse optical imaging
  • Biomedical Optics
  • Biophotonic
  • Clinical translation

Publications

<anyweb>http://icube-publis.unistra.fr/?author=gioux&title=&team=&national=&project=&year1=1979&year2=2015&fancybox-frame1418063188956=</anyweb>

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